Estudo histopatológico de leishmaniose com acometimento oral

Abstract

Leishmaniasis represents a group of diseases caused by different protozoan species of the genus Leishmania. Clinically they are divided into three main forms: visceral, cutaneous and mucocutaneous. Mucocutaneous leishmaniasis (MCL), the rarest of them, can cause nasal, oral, pharyngeal and laryngeal lesions. The diagnosis of MCL is made difficult by its clinical similarity with lesions that affect the orofacial complex mucosa and the low parasitic load present in this clinical form, which compromises the diagnosis through direct visualization of the parasite. Histopathology, although not confirming the disease, may favor the diagnosis. Due to the fact that MCL develops in the oral cavity region, area of operation of the dentist, the present study aims to identify the histopathological aspects involved in cases of oral involvement leishmaniasis. For this study we included all cases of leishmaniasis with oral involvement of two private laboratories of Governador Valadares. New sections were made from paraffin blocks that were stained with Hematoxylin-Eosin and Giemsa. The main findings were dense lymphocytic and lymphoplasmacytic infiltrates and presence of round body compatible with leishmania amastigotes within macrophage vacuoles.