Formulação de um autômato celular bidimensional para simulação da eletrofisiologia cardíaca

Abstract

Cardiovascular diseases are the leading cause of mortality worldwide, making it essential to develop computational tools to investigate the underlying mechanisms of these disorders. Models based on systems of differential equations are widely used due to their high accuracy, but they present high computational costs. In this context, this work proposes a cellular automaton to simulate the electrical propagation in the cardiac ventricular tissue, aiming to increase the efficiency of modeling this phenomenon. Data generated by the monodomain mathematical model are used to calibrate the restitution curves. The accuracy of the automaton is evaluated through tests that consider different fiber orientations and types of stimulation. The results show good agreement with biophysical simulations based on differential equations and reduced execution time compared to the monodomain model. Thus, the proposed model’s potential for applications in cardiac electrophysiology is highlighted.