Análise cromatográfica gasosa, acoplada a espectrômetro de massa, de pasta experimental contendo hidróxido de cálcio e óleo essencial de Rosmarinus Officinalis L.

Abstract

In the context of endodontic treatment, the biomechanical preparation of the root canal system aims to remove microorganisms and infected tissue, generally requiring the implementation of intracanal medications between sessions. Traditionally, the association of calcium hydroxide (Ca(OH)₂ ) with camphorated paramonochlorophenol (CMCP) is used, which increases antibacterial action but presents relevant cytotoxicity. Phytotherapy emerges as a therapeutic alternative, offering advantages such as absence of significant side effects, greater biocompatibility and lower cost. Rosmarinus officinalis, belonging to the Lamiaceae family, produces essential oils with antibacterial, anti-inflammatory and antioxidant properties, categorizing itself as a possible therapeutic alternative. The present study aimed to identify and quantify the components of an experimental paste containing calcium hydroxide and essential oil of R. officinalis L., through analysis with gas chromatography coupled to mass spectrometry (GC/MS). The R. officinalis L. oil was analyzed by the Analytical Chemistry Laboratory of ICE, Universidade Federal de Juiz de Fora. The experimental paste was prepared using 0,1g of analytical grade calcium hydroxide, 50 µL of essential oil and glycerin. The results showed that the experimental paste contains 32,04% Eucalyptol (1,8-cineole) and 54,40% Camphor, while the pure oil presented 23,42% Eucalyptol and 37,18% Camphor as the most prevalent compounds. It is concluded that the chemical composition of the experimental paste is almost entirely terpenes, resulting in antimicrobial activity, and that the interaction of the essential oil with calcium hydroxide did not significantly alter the oil composition regarding the expected therapeutic potential, revealing itself as a promising phytotherapeutic option for application in Endodontics.